It
has been widely acknowledged that proteins, large molecules, can direct our
body activities, organize our thoughts, and defend us against infection, thus
keeps us healthy. But if there occurs mutation, proteins can aslo make us in
trouble and even threaten our life.
Proteomics
is the study of the structure and function of proteins. And quantitative
proteomics involves identification and quantification of proteins in various
biological systems. On the one hand, protein quantification determines the
total protein concentration in a sample; on the other hand, protein
identification helps scientists to know better the structure and type of
certain proteins.
During
the last two decades, mass spectrometry has become a primary method for protein
identification from complex mixtures of biological origin. But the questions is
how can it help protein identification? After doing a research, the writer
found that it indeed helps protein identification in a couple of ways:
Firstly,
it can do help in the identification of protein binding partners that is to say
mass spectrometry can help identify the specific proteome for protein
interactions
Secondly,
it can help to characterize the purified protein samples: with mass
spectrometry, the right sequences can be ensured and the right location for the
modification can be guaranteed. Furthermore, it can also do some help in the
identification of impurities in the preparation.
Thirdly,
it can help work out protein post translational modification; with the help of
it, you can identify any modifications in the preparation.
To
name a few...
Since
the profound meaning of protein identification in the study of proteins, there
are a bunch of biotech companies worldwide that are offering protein
identification services. Creative Proteomics is an excellent one among them.
Current protein identification service in Creative Proteomics includes:
Digestion (in-gel or in solution), Molecular Weight Determination and Molecular
Weight Distribution of Peptides or Proteins, Sample Preparation, Purity
Analysis of Peptides or Proteins, Peptide Mass Fingerprinting (PMF), Sequence
Analysis of Peptides or Proteins (N-, C-), De Novo Protein Sequence Analysis,
Accurate Mass Determination, Shotgun Protein Identification, Membrane
Proteomics and Subcellular Proteomics.
About Creative Proteomics
Creative
Proteomics specializes in a full range of services to support various
proteome-related researches from identification of single proteins to
large-scale proteomic studies. We have one of the most advanced proteomics
platforms in the world and our staff scientists are experienced proteomics
professionals. Our proteome analysis platform provides protein separation,
characterization, identification and quantification services, featured with
high throughput and super-sensitivity. In addition, analyses of protein post-translational
modifications such as phosphorylation and glycosylation are available.
Contact Creative Proteomics
Address:
45-16 Ramsey Road, Shirley, NY 11967, USA
Tel:
1-631-624-4882
Website:
http://www.creative-proteomics.com
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